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July 26, 2026

mindbodygreen
The Long Game Logo

Good morning!

You’ve likely heard about peptides over the last year due to the rise of GLP-1s, but you may not know that the FDA recently formed a committee to review seven others for the possibility of being accessible through compounding pharmacies.

On one hand, there are still concerns over a lack of rigorous human clinical trials and safety data covering the purity of some peptides. On the other hand, some fear closing the door on compounding pushes consumers to seek peptides from untrustworthy sources.

Among those approved is BPC-157, which is used for tissue repair, gut healing, and reducing inflammation, and has already become quite popular despite lacking prior FDA approval. The committee’s votes can still be vetoed by the FDA, this was just a first step to get expert consensus.

Hit reply and tell me, what are your thoughts on peptide accessibility?

—Ailsa Cowell, M.S. health editor

Do you know someone who would love to have the latest longevity news in their inbox? You can share the newsletter with them here.

How leg strength impacts bone density

Strong legs are appealing for lots of reasons; running fast, hiking big hills, functional squats—the list goes on and on. But now we’re seeing leg strength is also an indicator of better hip bone density:¹

  • Study participants completed a one-rep max leg press to assess strength: the heaviest weight they could push with their legs just once.
  • Bone density was measured at the hip and lower spine using dual-energy x-ray absorptiometry (a DEXA scan).
  • They found that leg-press strength was strongly linked to hip bone density, and that connection held up even after accounting for age, sex, and body fat.

When you consider that breaking a hip over the age of 65 significantly increases the risk of death within the following year, it feels worthwhile to think about strength and bone density earlier in life.

+More bone support

  • Why we should sit less & move more for stronger bones
  • Study says eat this much protein for bone health
  • Everything you need to know about vitamin D & fractures

The antioxidants your liver craves

The antioxidants your liver craves

You already know your liver works hard. But most people don't think about supporting it until something feels off.

The sluggishness after a big weekend. The bloated, heavy feeling that lingers. The afternoon energy crash you can't explain. That's not just a bad day, that could be your liver asking for support.

liver detox+ is different. Glutathione and NAC to support cellular defense,* milk thistle and selenium to support liver and kidney detox,* vitamin C to restore antioxidant defenses.* It’s daily support that works with your life, not against it.*

Support your liver. Enjoy your life.*

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Healthy hormones

Healthy hormonesImage by svetikd / iStock
  • Why women should be tracking testosterone after 30
  • Creams, patches, pills… What is the right form of HRT for you?
  • 5 labs every woman over 40 should ask for
  • The latest research on early menopause symptoms & diagnosis
  • What a derm & hormone expert wants you to know about progesterone

Staying consistent = real results

Staying consistent = real results
  • Week 1+: Supports daily detox and antioxidant defenses *†
  • Week 4+: Supports liver and kidney function, promotes energy levels, and combats oxidative stress *†
  • Month 6+: Promotes long-term liver health with daily use.*†
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If you do one thing… think about your exhale

New research suggests the way we breathe may actually change what's happening inside our brains, influencing how we process information and even how we make decisions.³

  • Participants completed a series of decision-making tasks twice: once while breathing normally and once while intentionally making their exhales longer than their inhales.
  • A longer exhale shifted participants into a more parasympathetic, or "rest and digest," state and increased HRV.

By reacting with conscious breath first, we can create conditions for clearer thinking, greater emotional flexibility, and more intentional decision-making.

+Deep breaths

  • Your mouth impacts every breath, here’s how
  • Improve your memory with better nighttime breathing
  • Pelvic floor problems? It’s time to try this

That’s it for the long game—we hope you’re geared up for the week ahead of you.

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Credential Check


Ailsa Cowell, M.S.

Health Editor

Molly Knudsen, M.S., RDN

Expert Review

 

Citations

1 Medicine & Science in Sports

2 Nature Communications

3 Cell Press

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Just a heads-up: Everything in this newsletter is for general info only—not medical advice. We always recommend checking in with a healthcare professional before making any health decisions. Our product picks and reviews reflect our editors’ opinions unless we say otherwise. We sometimes link to other sites, but we’re not responsible for their content.

*These statements haven’t been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

†Benefits assume daily use and are evidence-based estimates rooted in clinical science at the ingredient level. Individual results may vary.
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Your Complete Guide To Strength Training — Built For Women, Backed By Experts

FEATURED ARTICLE · July 26th, 2026

FEATURED ARTICLE
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