Hi TLG readers,

I think a lot about how weight loss itself takes strain off nearly every organ. But part of using a GLP-1 works in ways that losing weight alone cannot explain.

• It helps your pancreas release insulin, it quiets the hormone glucagon, and it signals your brain that you are full.
• It also lowers inflammation and improves the lining of your blood vessels, and those effects reach well beyond your waistline.¹

Here is a point I want to be honest about, because you will see it overstated everywhere: People say these receptors sit directly inside your heart and kidneys, as if the drug plugs straight into each organ. The truth is more modest.

• The receptors mostly live in your blood vessels, your brain, and the pacemaker area of your heart, not in the working muscle of the heart or the filtering parts of the kidney.
• It calms inflammation, it steadies your blood vessels, and it improves your blood sugar and blood pressure.
• The organ benefits even when the drug is not acting on it directly. ^2,3,4,5

A lot of my work is in longevity, so this is a conversation I love having, though I hold it humbly. These protections are real and worth knowing about. For most women, though, they are still a bonus on top of the reason they came in.

—Jila Senemar, M.D., FACOG

+Metabolism & more

• Is it possible to naturally boost GLP-1?
• What to know about using a GLP-1 + HRT
• More ways GLP-1s go way beyond weight

Don’t forget to forward this email to a friend who wants to know more about GLP-1s.

There’s a reason leafy greens and root veggies are so good for heart health: They are high in dietary nitrates.

The body converts these into nitric oxide (NO), a critical molecule responsible for healthy blood flow that delivers oxygen and nutrients throughout the body.

Get an effective, concentrated dose with Berkeley Life Nitric Oxide Support.*

One study found that users taking it experienced:

• 378% increase in nitrate levels indicating significantly improved NO production*
• 12.5 mmHg reduction in systolic blood pressure showing improved cardiovascular health*
• 28% improvement in circulation as measured by the gold standard measure of blood flow*

But what does this mean for your day-to-day life? Obviously improved heart health—but Nitric Oxide Support is also shown to deliver more sustained energy, quicker recovery, sharper cognitive function, and optimal performance.*

+ Learn more

• Did you know that NO levels decline by half by age 40?
• Bundle Nitric Support with NO test strips to track your levels
• Support NO levels for a full 24 hours

• Research found a winning ingredient for both hair & skin health
• Pay attention to these 6 vitamins to boost hair growth
• Other ways to make your hair grow faster
• The ultimate guide to loving your curly hair
• This ancient hair treatment is rich in antioxidants

Nitric Oxide supports the systems that drive how you feel, perform, and age: Berkeley Life Nitric Oxide Support's clinical trial subjects showed a 300% increase in capacity to produce energy after 3 months.* Plus, vitamin B12, thiamin (B1), and magnesium all support cellular energy metabolism.*

Cancer and Alzheimer’s (AD) are two words we all hope never to hear. And while they share many of the same risk factors, there is an interesting paradox:⁷

• The risk of AD in cancer patients is reduced 25-35%.
• The risk of cancer in AD patients is reduced 50%.
• Studies have found having a prior cancer diagnosis was associated with a lower likelihood of neurofibrillary tangles and amyloid plaques linked to AD.
• Research has also found extensive brain tumor infiltration was linked to decreased signs of AD pathology.

One possible explanation is an evolutionary tradeoff due to the fact that the processes behind cancer and AD work in opposite directions. Cancer means increased cell proliferation and avoids immune destruction; AD means neuronal cell death and increases immune activation.

Obviously there is still a lot more to learn about this relationship, but understanding it could lead to future innovations for reducing the burden of each.

+What we know

• Lifestyle habits linked to better post-cancer outcomes
• This new treatment will revolutionize pancreatic cancer treatment
• Women with Alzheimer’s may be deficient in these nutrients

That’s it forthe long game—thanks for playing. Have a great weekend!